pglA protein (Neisseria meningitidis) - STRING interaction network

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Score

pglA

Glycosyltransferase (376 aa)

Predicted Functional Partners:

pglB

0.989

lgtA

0.849

pglD

0.845

pglC

0.829

lgtF

0.787

galE

0.784

lgtB

0.708

NMB0846

0.682

lgtE

0.681

pgl

0.681

Your Current Organism:

Neisseria meningitidis

NCBI taxonomy Id: 122586
Other names: Diplokokkus intracellularis meningitidis, Micrococcus intracellularis, Micrococcus meningitidis, Micrococcus meningitidis cerebrospinalis, N. meningitidis, N. meningitidis MC58, N. meningitidis serogroup B, Neisseria meningitidis, Neisseria meningitidis (group B), Neisseria meningitidis (serogroup B), Neisseria meningitidis MC58, Neisseria meningitidis group B, Neisseria meningitidis serogroup B, Neisseria meningitidis serogroup B strain MC58, Neisseria weichselbaumii

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NMB0846	lgtA	NMB0846	NMB1929	LPS biosynthesis protein-like protein	lacto-N-neotetraose biosynthesis glycosyl transferase	0.529
NMB0846	lgtF	NMB0846	NMB1704	LPS biosynthesis protein-like protein	Beta-1,4-glucosyltransferase	0.495
NMB0846	pglA	NMB0846	NMB0218	LPS biosynthesis protein-like protein	Glycosyltransferase	0.682
NMB0846	pglB	NMB0846	NMB1820	LPS biosynthesis protein-like protein	Pilin glycosylation protein PglB	0.895
NMB0846	pglC	NMB0846	NMB1821	LPS biosynthesis protein-like protein	Pilin glycosylation protein	0.480
NMB0846	pglD	NMB0846	NMB1822	LPS biosynthesis protein-like protein	Pilin glycosylation protein	0.444
galE	lgtA	NMB0064	NMB1929	UDP-glucose 4-epimerase; Involved in the metabolism of galactose. Plays an essential role in the incorporation of galactose into meningococcal lipopolysaccharide surface molecules, which are important for pathogenesis. Catalyzes the conversion of UDP- galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD	lacto-N-neotetraose biosynthesis glycosyl transferase	0.719
galE	lgtB	NMB0064	NMB1928	UDP-glucose 4-epimerase; Involved in the metabolism of galactose. Plays an essential role in the incorporation of galactose into meningococcal lipopolysaccharide surface molecules, which are important for pathogenesis. Catalyzes the conversion of UDP- galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD	lacto-N-neotetraose biosynthesis glycosyl transferase LgtB; Adds the second galactose to the lacto-N-tetraose chain in lipooligosaccharide (LOS)	0.643
galE	lgtE	NMB0064	NMB1926	UDP-glucose 4-epimerase; Involved in the metabolism of galactose. Plays an essential role in the incorporation of galactose into meningococcal lipopolysaccharide surface molecules, which are important for pathogenesis. Catalyzes the conversion of UDP- galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD	lacto-N-neotetraose biosynthesis glycosyl transferase LgtE; Adds the first galactose to the lacto-N-tetraose chain in lipooligosaccharide (LOS)	0.593
galE	lgtF	NMB0064	NMB1704	UDP-glucose 4-epimerase; Involved in the metabolism of galactose. Plays an essential role in the incorporation of galactose into meningococcal lipopolysaccharide surface molecules, which are important for pathogenesis. Catalyzes the conversion of UDP- galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD	Beta-1,4-glucosyltransferase	0.786
galE	pglA	NMB0064	NMB0218	UDP-glucose 4-epimerase; Involved in the metabolism of galactose. Plays an essential role in the incorporation of galactose into meningococcal lipopolysaccharide surface molecules, which are important for pathogenesis. Catalyzes the conversion of UDP- galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD	Glycosyltransferase	0.784
galE	pglB	NMB0064	NMB1820	UDP-glucose 4-epimerase; Involved in the metabolism of galactose. Plays an essential role in the incorporation of galactose into meningococcal lipopolysaccharide surface molecules, which are important for pathogenesis. Catalyzes the conversion of UDP- galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD	Pilin glycosylation protein PglB	0.821
galE	pglC	NMB0064	NMB1821	UDP-glucose 4-epimerase; Involved in the metabolism of galactose. Plays an essential role in the incorporation of galactose into meningococcal lipopolysaccharide surface molecules, which are important for pathogenesis. Catalyzes the conversion of UDP- galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD	Pilin glycosylation protein	0.504
galE	pglD	NMB0064	NMB1822	UDP-glucose 4-epimerase; Involved in the metabolism of galactose. Plays an essential role in the incorporation of galactose into meningococcal lipopolysaccharide surface molecules, which are important for pathogenesis. Catalyzes the conversion of UDP- galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD	Pilin glycosylation protein	0.766
lgtA	NMB0846	NMB1929	NMB0846	lacto-N-neotetraose biosynthesis glycosyl transferase	LPS biosynthesis protein-like protein	0.529
lgtA	galE	NMB1929	NMB0064	lacto-N-neotetraose biosynthesis glycosyl transferase	UDP-glucose 4-epimerase; Involved in the metabolism of galactose. Plays an essential role in the incorporation of galactose into meningococcal lipopolysaccharide surface molecules, which are important for pathogenesis. Catalyzes the conversion of UDP- galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD	0.719
lgtA	lgtB	NMB1929	NMB1928	lacto-N-neotetraose biosynthesis glycosyl transferase	lacto-N-neotetraose biosynthesis glycosyl transferase LgtB; Adds the second galactose to the lacto-N-tetraose chain in lipooligosaccharide (LOS)	0.925
lgtA	lgtE	NMB1929	NMB1926	lacto-N-neotetraose biosynthesis glycosyl transferase	lacto-N-neotetraose biosynthesis glycosyl transferase LgtE; Adds the first galactose to the lacto-N-tetraose chain in lipooligosaccharide (LOS)	0.892
lgtA	lgtF	NMB1929	NMB1704	lacto-N-neotetraose biosynthesis glycosyl transferase	Beta-1,4-glucosyltransferase	0.718
lgtA	pglA	NMB1929	NMB0218	lacto-N-neotetraose biosynthesis glycosyl transferase	Glycosyltransferase	0.849

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