node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
legI_1 | neuA | Cjejjejuni_010100006055 | Cjejjejuni_010100006070 | N,N’-diacetyllegionaminic acid synthase (EC-2.5.1.101) | N-acylneuraminate cytidylyltransferase (EC-2.7.7.43) | 0.999 |
legI_1 | pglE | Cjejjejuni_010100006055 | Cjejjejuni_010100005940 | N,N’-diacetyllegionaminic acid synthase (EC-2.5.1.101) | UDP-N-acetylbacillosamine transaminase (EC-2.6.1.34) | 0.684 |
legI_1 | pglF | Cjejjejuni_010100006055 | Cjejjejuni_010100005935 | N,N’-diacetyllegionaminic acid synthase (EC-2.5.1.101) | UDP-N-acetyl-alpha-D-glucosamine C6 dehydratase (EC-4.2.1.135) | 0.775 |
legI_1 | pseA | Cjejjejuni_010100006055 | Cjejjejuni_010100007000 | N,N’-diacetyllegionaminic acid synthase (EC-2.5.1.101) | Flagellin modification protein, PseA | 0.748 |
legI_1 | pseB | Cjejjejuni_010100006055 | Cjejjejuni_010100006870 | N,N’-diacetyllegionaminic acid synthase (EC-2.5.1.101) | UDP-GlcNAc-inverting 4,6-dehydratase; Catalyzes the first step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Has both C6 dehydratase and C5 epimerase activities that result in the production of both UDP-2-acetamido-2,6-dideoxy- beta-L-arabino-4-hexulose and UDP-2-acetamido-2,6-dideoxy-alpha-D- xylo-4-hexulose | 0.886 |
legI_1 | pseC | Cjejjejuni_010100006055 | Cjejjejuni_010100006875 | N,N’-diacetyllegionaminic acid synthase (EC-2.5.1.101) | Pseudaminic acid biosynthesis protein C; Catalyzes the second step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Uses UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4- hexulose as substrate producing UDP-4-amino-4,6-dideoxy-beta-L- AltNAc | 0.680 |
legI_1 | pseD | Cjejjejuni_010100006055 | Cjejjejuni_010100007025 | N,N’-diacetyllegionaminic acid synthase (EC-2.5.1.101) | PseD | 0.724 |
legI_1 | pseF | Cjejjejuni_010100006055 | Cjejjejuni_010100006975 | N,N’-diacetyllegionaminic acid synthase (EC-2.5.1.101) | CMP-N,N’-diacetyllegionaminic acid synthase (EC-2.7.7.82); Catalyzes the final step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Mediates the activation of pseudaminic acid with CMP by forming CMP-pseudaminic acid (By similarity) | 0.997 |
legI_1 | pseG | Cjejjejuni_010100006055 | Cjejjejuni_010100006980 | N,N’-diacetyllegionaminic acid synthase (EC-2.5.1.101) | UDP-2,4-diacetamido-2,4, 6-trideoxy-beta-L-altropyranose hydrolase (EC-3.6.1.57); Nucleotide sugar hydrolase that catalyzes the fourth step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Mediates the removal of UDP from C-1 of UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L- altropyranose forming 2,4-diacetamido-2,4,6-trideoxy-beta-L- altropyranose (By similarity) | 0.884 |
legI_1 | pseH | Cjejjejuni_010100006055 | Cjejjejuni_010100006985 | N,N’-diacetyllegionaminic acid synthase (EC-2.5.1.101) | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase (EC-2.3.1.202); Catalyzes the third step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Mediates N-4 acetylation of UDP-4-amino-4,6-dideoxy- beta-L-AltNAc to form UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L- altropyranose (By similarity) | 0.704 |
neuA | legI_1 | Cjejjejuni_010100006070 | Cjejjejuni_010100006055 | N-acylneuraminate cytidylyltransferase (EC-2.7.7.43) | N,N’-diacetyllegionaminic acid synthase (EC-2.5.1.101) | 0.999 |
neuA | pglE | Cjejjejuni_010100006070 | Cjejjejuni_010100005940 | N-acylneuraminate cytidylyltransferase (EC-2.7.7.43) | UDP-N-acetylbacillosamine transaminase (EC-2.6.1.34) | 0.676 |
neuA | pglF | Cjejjejuni_010100006070 | Cjejjejuni_010100005935 | N-acylneuraminate cytidylyltransferase (EC-2.7.7.43) | UDP-N-acetyl-alpha-D-glucosamine C6 dehydratase (EC-4.2.1.135) | 0.628 |
neuA | pseA | Cjejjejuni_010100006070 | Cjejjejuni_010100007000 | N-acylneuraminate cytidylyltransferase (EC-2.7.7.43) | Flagellin modification protein, PseA | 0.706 |
neuA | pseB | Cjejjejuni_010100006070 | Cjejjejuni_010100006870 | N-acylneuraminate cytidylyltransferase (EC-2.7.7.43) | UDP-GlcNAc-inverting 4,6-dehydratase; Catalyzes the first step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Has both C6 dehydratase and C5 epimerase activities that result in the production of both UDP-2-acetamido-2,6-dideoxy- beta-L-arabino-4-hexulose and UDP-2-acetamido-2,6-dideoxy-alpha-D- xylo-4-hexulose | 0.693 |
neuA | pseC | Cjejjejuni_010100006070 | Cjejjejuni_010100006875 | N-acylneuraminate cytidylyltransferase (EC-2.7.7.43) | Pseudaminic acid biosynthesis protein C; Catalyzes the second step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Uses UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4- hexulose as substrate producing UDP-4-amino-4,6-dideoxy-beta-L- AltNAc | 0.675 |
neuA | pseD | Cjejjejuni_010100006070 | Cjejjejuni_010100007025 | N-acylneuraminate cytidylyltransferase (EC-2.7.7.43) | PseD | 0.610 |
neuA | pseG | Cjejjejuni_010100006070 | Cjejjejuni_010100006980 | N-acylneuraminate cytidylyltransferase (EC-2.7.7.43) | UDP-2,4-diacetamido-2,4, 6-trideoxy-beta-L-altropyranose hydrolase (EC-3.6.1.57); Nucleotide sugar hydrolase that catalyzes the fourth step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Mediates the removal of UDP from C-1 of UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L- altropyranose forming 2,4-diacetamido-2,4,6-trideoxy-beta-L- altropyranose (By similarity) | 0.662 |
neuA | pseH | Cjejjejuni_010100006070 | Cjejjejuni_010100006985 | N-acylneuraminate cytidylyltransferase (EC-2.7.7.43) | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase (EC-2.3.1.202); Catalyzes the third step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Mediates N-4 acetylation of UDP-4-amino-4,6-dideoxy- beta-L-AltNAc to form UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L- altropyranose (By similarity) | 0.635 |
pglE | legI_1 | Cjejjejuni_010100005940 | Cjejjejuni_010100006055 | UDP-N-acetylbacillosamine transaminase (EC-2.6.1.34) | N,N’-diacetyllegionaminic acid synthase (EC-2.5.1.101) | 0.684 |