| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| glmU | legI_1 | Cjejjejuni_010100004315 | Cjejjejuni_010100006055 | Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain | N,N’-diacetyllegionaminic acid synthase (EC-2.5.1.101) | 0.631 |
| glmU | murA | Cjejjejuni_010100004315 | Cjejjejuni_010100004525 | Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain | UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC-2.5.1.7); Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine | 0.949 |
| glmU | pglF | Cjejjejuni_010100004315 | Cjejjejuni_010100005935 | Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain | UDP-N-acetyl-alpha-D-glucosamine C6 dehydratase (EC-4.2.1.135) | 0.881 |
| glmU | pseB | Cjejjejuni_010100004315 | Cjejjejuni_010100006870 | Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain | UDP-GlcNAc-inverting 4,6-dehydratase; Catalyzes the first step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Has both C6 dehydratase and C5 epimerase activities that result in the production of both UDP-2-acetamido-2,6-dideoxy- beta-L-arabino-4-hexulose and UDP-2-acetamido-2,6-dideoxy-alpha-D- xylo-4-hexulose | 0.881 |
| glmU | siaA | Cjejjejuni_010100004315 | Cjejjejuni_010100006060 | Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain | UDP-N-acetylglucosamine 2-epimerase (EC-3.2.1.183) | 0.857 |
| legI_1 | glmU | Cjejjejuni_010100006055 | Cjejjejuni_010100004315 | N,N’-diacetyllegionaminic acid synthase (EC-2.5.1.101) | Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain | 0.631 |
| legI_1 | pglE | Cjejjejuni_010100006055 | Cjejjejuni_010100005940 | N,N’-diacetyllegionaminic acid synthase (EC-2.5.1.101) | UDP-N-acetylbacillosamine transaminase (EC-2.6.1.34) | 0.684 |
| legI_1 | pglF | Cjejjejuni_010100006055 | Cjejjejuni_010100005935 | N,N’-diacetyllegionaminic acid synthase (EC-2.5.1.101) | UDP-N-acetyl-alpha-D-glucosamine C6 dehydratase (EC-4.2.1.135) | 0.775 |
| legI_1 | pseB | Cjejjejuni_010100006055 | Cjejjejuni_010100006870 | N,N’-diacetyllegionaminic acid synthase (EC-2.5.1.101) | UDP-GlcNAc-inverting 4,6-dehydratase; Catalyzes the first step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Has both C6 dehydratase and C5 epimerase activities that result in the production of both UDP-2-acetamido-2,6-dideoxy- beta-L-arabino-4-hexulose and UDP-2-acetamido-2,6-dideoxy-alpha-D- xylo-4-hexulose | 0.886 |
| legI_1 | pseC | Cjejjejuni_010100006055 | Cjejjejuni_010100006875 | N,N’-diacetyllegionaminic acid synthase (EC-2.5.1.101) | Pseudaminic acid biosynthesis protein C; Catalyzes the second step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Uses UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4- hexulose as substrate producing UDP-4-amino-4,6-dideoxy-beta-L- AltNAc | 0.680 |
| legI_1 | pseG | Cjejjejuni_010100006055 | Cjejjejuni_010100006980 | N,N’-diacetyllegionaminic acid synthase (EC-2.5.1.101) | UDP-2,4-diacetamido-2,4, 6-trideoxy-beta-L-altropyranose hydrolase (EC-3.6.1.57); Nucleotide sugar hydrolase that catalyzes the fourth step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Mediates the removal of UDP from C-1 of UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L- altropyranose forming 2,4-diacetamido-2,4,6-trideoxy-beta-L- altropyranose (By similarity) | 0.884 |
| legI_1 | pseH | Cjejjejuni_010100006055 | Cjejjejuni_010100006985 | N,N’-diacetyllegionaminic acid synthase (EC-2.5.1.101) | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase (EC-2.3.1.202); Catalyzes the third step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Mediates N-4 acetylation of UDP-4-amino-4,6-dideoxy- beta-L-AltNAc to form UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L- altropyranose (By similarity) | 0.704 |
| legI_1 | siaA | Cjejjejuni_010100006055 | Cjejjejuni_010100006060 | N,N’-diacetyllegionaminic acid synthase (EC-2.5.1.101) | UDP-N-acetylglucosamine 2-epimerase (EC-3.2.1.183) | 0.999 |
| legI_1 | wbpE | Cjejjejuni_010100006055 | Cjejjejuni_010100002665 | N,N’-diacetyllegionaminic acid synthase (EC-2.5.1.101) | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase (EC-2.6.1.98) | 0.519 |
| murA | glmU | Cjejjejuni_010100004525 | Cjejjejuni_010100004315 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC-2.5.1.7); Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine | Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain | 0.949 |
| murA | pglF | Cjejjejuni_010100004525 | Cjejjejuni_010100005935 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC-2.5.1.7); Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine | UDP-N-acetyl-alpha-D-glucosamine C6 dehydratase (EC-4.2.1.135) | 0.883 |
| murA | pseB | Cjejjejuni_010100004525 | Cjejjejuni_010100006870 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC-2.5.1.7); Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine | UDP-GlcNAc-inverting 4,6-dehydratase; Catalyzes the first step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Has both C6 dehydratase and C5 epimerase activities that result in the production of both UDP-2-acetamido-2,6-dideoxy- beta-L-arabino-4-hexulose and UDP-2-acetamido-2,6-dideoxy-alpha-D- xylo-4-hexulose | 0.883 |
| murA | siaA | Cjejjejuni_010100004525 | Cjejjejuni_010100006060 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC-2.5.1.7); Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine | UDP-N-acetylglucosamine 2-epimerase (EC-3.2.1.183) | 0.915 |
| pglE | legI_1 | Cjejjejuni_010100005940 | Cjejjejuni_010100006055 | UDP-N-acetylbacillosamine transaminase (EC-2.6.1.34) | N,N’-diacetyllegionaminic acid synthase (EC-2.5.1.101) | 0.684 |
| pglE | pglF | Cjejjejuni_010100005940 | Cjejjejuni_010100005935 | UDP-N-acetylbacillosamine transaminase (EC-2.6.1.34) | UDP-N-acetyl-alpha-D-glucosamine C6 dehydratase (EC-4.2.1.135) | 0.978 |
