| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cj1298 | Cj1320 | Cj1298 | Cj1320 | N-acetyltransferase | DegT family aminotransferase | 0.489 |
| Cj1298 | pseB | Cj1298 | Cj1293 | N-acetyltransferase | UDP-GlcNAc-specific C4,6 dehydratase/C5 epimerase; Catalyzes the first step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Has both C6 dehydratase and C5 epimerase activities that result in the production of both UDP-2-acetamido-2,6-dideoxy- beta-L-arabino-4-hexulose and UDP-2-acetamido-2,6-dideoxy-alpha-D- xylo-4-hexulose | 0.919 |
| Cj1298 | pseC | Cj1298 | Cj1294 | N-acetyltransferase | C4 aminotransferase; Catalyzes the second step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Uses UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4- hexulose as substrate producing UDP-4-amino-4,6-dideoxy-beta-L- AltNAc | 0.910 |
| Cj1320 | Cj1298 | Cj1320 | Cj1298 | DegT family aminotransferase | N-acetyltransferase | 0.489 |
| Cj1320 | legG | Cj1320 | Cj1328 | DegT family aminotransferase | UDP-N-acetylglucosamine 2-epimerase; Involved in biosynthesis of legionaminic acid (5,7- diamino-3,5,7,9-tetradeoxy-D-glycero-D-galacto-non-2-ulosonic acid)(Leg), a sialic acid-like derivative that is incorporated into flagellin via O-linkage to Ser/Thr. Catalyzes the conversion of GDP-N,N’-diacetylbacillosamine (Bac2Ac4Ac) into 2,4- diacetamido-2,4,6-trideoxymannose and GDP. It can also use UDP- N,N’-diacetylbacillosamine however it generates small quantities of 2,4-diacetamido-2,4,6-trideoxymannose | 0.987 |
| Cj1320 | neuC1 | Cj1320 | Cj1142 | DegT family aminotransferase | UDP-N-acetylglucosamine 2-epimerase | 0.523 |
| Cj1320 | pglF | Cj1320 | Cj1120c | DegT family aminotransferase | UDP-GlcNAc C4,6 dehydratase; C6 dehydratase involved in the bacillosamine biosynthesis pathway by generating UDP-2-acetamido-2,6-dideoxy- alpha-D-xylo-4-hexulose from UDP-N-acetyl-alpha-D-glucosamine. Involved in the N-linked protein glycosylation pathway | 0.948 |
| Cj1320 | pseB | Cj1320 | Cj1293 | DegT family aminotransferase | UDP-GlcNAc-specific C4,6 dehydratase/C5 epimerase; Catalyzes the first step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Has both C6 dehydratase and C5 epimerase activities that result in the production of both UDP-2-acetamido-2,6-dideoxy- beta-L-arabino-4-hexulose and UDP-2-acetamido-2,6-dideoxy-alpha-D- xylo-4-hexulose | 0.949 |
| Cj1320 | pseC | Cj1320 | Cj1294 | DegT family aminotransferase | C4 aminotransferase; Catalyzes the second step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Uses UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4- hexulose as substrate producing UDP-4-amino-4,6-dideoxy-beta-L- AltNAc | 0.441 |
| Cj1320 | pseG | Cj1320 | Cj1312 | DegT family aminotransferase | Nucleotidase specific for PseC product,UDP-4-amino-4,6-dideoxy-beta-L-AltNAc; Nucleotide sugar hydrolase that catalyzes the fourth step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Mediates the removal of UDP from C-1 of UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L- altropyranose forming 2,4-diacetamido-2,4,6-trideoxy-beta-L- altropyranose | 0.570 |
| Cj1320 | pseH | Cj1320 | Cj1313 | DegT family aminotransferase | N-acetyltransferase specific for PseC product,UDP-4-amino-4,6-dideoxy-beta-L-AltNAc; Catalyzes the third step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Mediates N-4 acetylation of UDP-4-amino-4,6-dideoxy- beta-L-AltNAc to form UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L- altropyranose (By similarity) | 0.906 |
| Cj1320 | pseI | Cj1320 | Cj1317 | DegT family aminotransferase | Pse synthetase; Catalyzes the fifth step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Catalyzes the condensation of phosphoenolpyruvate with 2,4-diacetamido-2,4,6-trideoxy-beta-l-altropyranose, forming pseudaminic acid | 0.969 |
| legG | Cj1320 | Cj1328 | Cj1320 | UDP-N-acetylglucosamine 2-epimerase; Involved in biosynthesis of legionaminic acid (5,7- diamino-3,5,7,9-tetradeoxy-D-glycero-D-galacto-non-2-ulosonic acid)(Leg), a sialic acid-like derivative that is incorporated into flagellin via O-linkage to Ser/Thr. Catalyzes the conversion of GDP-N,N’-diacetylbacillosamine (Bac2Ac4Ac) into 2,4- diacetamido-2,4,6-trideoxymannose and GDP. It can also use UDP- N,N’-diacetylbacillosamine however it generates small quantities of 2,4-diacetamido-2,4,6-trideoxymannose | DegT family aminotransferase | 0.987 |
| legG | pglE | Cj1328 | Cj1121c | UDP-N-acetylglucosamine 2-epimerase; Involved in biosynthesis of legionaminic acid (5,7- diamino-3,5,7,9-tetradeoxy-D-glycero-D-galacto-non-2-ulosonic acid)(Leg), a sialic acid-like derivative that is incorporated into flagellin via O-linkage to Ser/Thr. Catalyzes the conversion of GDP-N,N’-diacetylbacillosamine (Bac2Ac4Ac) into 2,4- diacetamido-2,4,6-trideoxymannose and GDP. It can also use UDP- N,N’-diacetylbacillosamine however it generates small quantities of 2,4-diacetamido-2,4,6-trideoxymannose | UDP-4-keto-6-deoxy-GlcNAc C4 aminotransferase; Aminotransferase involved in the bacillosamine biosynthesis pathway by producing UDP-4-amino-4,6-dideoxy-alpha-D- GlcNAc (UDP-2-acetamido-4-amino-2,4,6-trideoxy-alpha-D- glucopyranose), a precursor used in the production of the glycan component 2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose. Required for host colonization and virulence. Involved in the N- linked protein glycosylation pathway | 0.523 |
| legG | pglF | Cj1328 | Cj1120c | UDP-N-acetylglucosamine 2-epimerase; Involved in biosynthesis of legionaminic acid (5,7- diamino-3,5,7,9-tetradeoxy-D-glycero-D-galacto-non-2-ulosonic acid)(Leg), a sialic acid-like derivative that is incorporated into flagellin via O-linkage to Ser/Thr. Catalyzes the conversion of GDP-N,N’-diacetylbacillosamine (Bac2Ac4Ac) into 2,4- diacetamido-2,4,6-trideoxymannose and GDP. It can also use UDP- N,N’-diacetylbacillosamine however it generates small quantities of 2,4-diacetamido-2,4,6-trideoxymannose | UDP-GlcNAc C4,6 dehydratase; C6 dehydratase involved in the bacillosamine biosynthesis pathway by generating UDP-2-acetamido-2,6-dideoxy- alpha-D-xylo-4-hexulose from UDP-N-acetyl-alpha-D-glucosamine. Involved in the N-linked protein glycosylation pathway | 0.868 |
| legG | pseB | Cj1328 | Cj1293 | UDP-N-acetylglucosamine 2-epimerase; Involved in biosynthesis of legionaminic acid (5,7- diamino-3,5,7,9-tetradeoxy-D-glycero-D-galacto-non-2-ulosonic acid)(Leg), a sialic acid-like derivative that is incorporated into flagellin via O-linkage to Ser/Thr. Catalyzes the conversion of GDP-N,N’-diacetylbacillosamine (Bac2Ac4Ac) into 2,4- diacetamido-2,4,6-trideoxymannose and GDP. It can also use UDP- N,N’-diacetylbacillosamine however it generates small quantities of 2,4-diacetamido-2,4,6-trideoxymannose | UDP-GlcNAc-specific C4,6 dehydratase/C5 epimerase; Catalyzes the first step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Has both C6 dehydratase and C5 epimerase activities that result in the production of both UDP-2-acetamido-2,6-dideoxy- beta-L-arabino-4-hexulose and UDP-2-acetamido-2,6-dideoxy-alpha-D- xylo-4-hexulose | 0.968 |
| legG | pseC | Cj1328 | Cj1294 | UDP-N-acetylglucosamine 2-epimerase; Involved in biosynthesis of legionaminic acid (5,7- diamino-3,5,7,9-tetradeoxy-D-glycero-D-galacto-non-2-ulosonic acid)(Leg), a sialic acid-like derivative that is incorporated into flagellin via O-linkage to Ser/Thr. Catalyzes the conversion of GDP-N,N’-diacetylbacillosamine (Bac2Ac4Ac) into 2,4- diacetamido-2,4,6-trideoxymannose and GDP. It can also use UDP- N,N’-diacetylbacillosamine however it generates small quantities of 2,4-diacetamido-2,4,6-trideoxymannose | C4 aminotransferase; Catalyzes the second step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Uses UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4- hexulose as substrate producing UDP-4-amino-4,6-dideoxy-beta-L- AltNAc | 0.758 |
| legG | pseI | Cj1328 | Cj1317 | UDP-N-acetylglucosamine 2-epimerase; Involved in biosynthesis of legionaminic acid (5,7- diamino-3,5,7,9-tetradeoxy-D-glycero-D-galacto-non-2-ulosonic acid)(Leg), a sialic acid-like derivative that is incorporated into flagellin via O-linkage to Ser/Thr. Catalyzes the conversion of GDP-N,N’-diacetylbacillosamine (Bac2Ac4Ac) into 2,4- diacetamido-2,4,6-trideoxymannose and GDP. It can also use UDP- N,N’-diacetylbacillosamine however it generates small quantities of 2,4-diacetamido-2,4,6-trideoxymannose | Pse synthetase; Catalyzes the fifth step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Catalyzes the condensation of phosphoenolpyruvate with 2,4-diacetamido-2,4,6-trideoxy-beta-l-altropyranose, forming pseudaminic acid | 0.945 |
| neuC1 | Cj1320 | Cj1142 | Cj1320 | UDP-N-acetylglucosamine 2-epimerase | DegT family aminotransferase | 0.523 |
| neuC1 | pglE | Cj1142 | Cj1121c | UDP-N-acetylglucosamine 2-epimerase | UDP-4-keto-6-deoxy-GlcNAc C4 aminotransferase; Aminotransferase involved in the bacillosamine biosynthesis pathway by producing UDP-4-amino-4,6-dideoxy-alpha-D- GlcNAc (UDP-2-acetamido-4-amino-2,4,6-trideoxy-alpha-D- glucopyranose), a precursor used in the production of the glycan component 2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose. Required for host colonization and virulence. Involved in the N- linked protein glycosylation pathway | 0.523 |
