glmS protein (Methanococcus maripaludis S2) - STRING interaction network

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glmS

Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (602 aa)

Predicted Functional Partners:

glmM

0.998

pgi

0.989

carA

0.986

carB

0.986

MMP1076

0.970

glnA

0.966

guaB

0.962

manB

0.957

purF

0.930

MMP0287

0.909

Your Current Organism:

Methanococcus maripaludis S2

NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis S2, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MMP0287	carA	MMP0287	MMP1589	CBS domain-containing protein	Carbamoyl phosphate synthase small subunit	0.551
MMP0287	carB	MMP0287	MMP1013	CBS domain-containing protein	Carbamoyl-phosphate synthase large subunit	0.508
MMP0287	glmM	MMP0287	MMP1077	CBS domain-containing protein	Phosphoglucomutase/phosphomannomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. Also catalyzes the isomerization of glucose-1-phosphate to glucose-6-phosphate, but at a 5-fold lower rate	0.793
MMP0287	glmS	MMP0287	MMP1680	CBS domain-containing protein	Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	0.909
MMP0287	guaB	MMP0287	MMP0133	CBS domain-containing protein	IMP dehydrogenase (EC-1.1.1.205)	0.996
MMP0287	manB	MMP0287	MMP1372	CBS domain-containing protein	Phosphomannomutase	0.793
MMP0287	pgi	MMP0287	MMP1295	CBS domain-containing protein	Glucose-6-phosphate isomerase	0.535
MMP0287	purF	MMP0287	MMP1146	CBS domain-containing protein	Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	0.851
MMP1076	carB	MMP1076	MMP1013	Hexapeptide repeat-containing transferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcNAc and pyrophosphate (By similarity)	Carbamoyl-phosphate synthase large subunit	0.482
MMP1076	glmM	MMP1076	MMP1077	Hexapeptide repeat-containing transferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcNAc and pyrophosphate (By similarity)	Phosphoglucomutase/phosphomannomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. Also catalyzes the isomerization of glucose-1-phosphate to glucose-6-phosphate, but at a 5-fold lower rate	0.999
MMP1076	glmS	MMP1076	MMP1680	Hexapeptide repeat-containing transferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcNAc and pyrophosphate (By similarity)	Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	0.970
MMP1076	manB	MMP1076	MMP1372	Hexapeptide repeat-containing transferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcNAc and pyrophosphate (By similarity)	Phosphomannomutase	0.993
MMP1076	pgi	MMP1076	MMP1295	Hexapeptide repeat-containing transferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcNAc and pyrophosphate (By similarity)	Glucose-6-phosphate isomerase	0.868
carA	MMP0287	MMP1589	MMP0287	Carbamoyl phosphate synthase small subunit	CBS domain-containing protein	0.551
carA	carB	MMP1589	MMP1013	Carbamoyl phosphate synthase small subunit	Carbamoyl-phosphate synthase large subunit	0.999
carA	glmS	MMP1589	MMP1680	Carbamoyl phosphate synthase small subunit	Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	0.986
carA	glnA	MMP1589	MMP1206	Carbamoyl phosphate synthase small subunit	Glutamine synthetase	0.943
carA	guaB	MMP1589	MMP0133	Carbamoyl phosphate synthase small subunit	IMP dehydrogenase (EC-1.1.1.205)	0.935
carA	purF	MMP1589	MMP1146	Carbamoyl phosphate synthase small subunit	Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	0.976
carB	MMP0287	MMP1013	MMP0287	Carbamoyl-phosphate synthase large subunit	CBS domain-containing protein	0.508

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