node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
hisF2 | wbpA | PA3151 | PA3159 | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) | UDP-N-acetyl-d-glucosamine 6-dehydrogenase; Plays a role in the biosynthesis of B-band O antigen for serotype O5. Catalyzes the C-6 dehydrogenation of UDP-D-GlcNAc to UDP-N-acetylglucosaminuronic acid (UDP-D-GlcNAcA) | 0.575 |
hisF2 | wbpB | PA3151 | PA3158 | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) | UDP-2-acetamido-2-deoxy-d-glucuronic acid 3-dehydrogenase WbpB; Plays a role in the biosynthesis of B-band O antigen for serotype O5. Catalyzes the NAD-dependent oxidation of UDP-N- acetylglucosaminuronic acid (UDP-D-GlcNAcA) to UDP-2-acetamido-2- deoxy-3-oxo-D-glucuronic acid (UDP-3-oxo-D-GlcNAcA). Can not use UDP-GlcNAc or UDP-GalNAc as the nucleotide sugar substrate, and can use only poorly UDP-D-glucuronic acid (UDP-GlcA). Undergoes an NAD(+) recycling mechanism using 2-oxoglutarate as an oxidant | 0.787 |
hisF2 | wbpD | PA3151 | PA3156 | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) | UDP-2-acetamido-3-amino-23-dideoxy-d-glucuronic acid N-acetyltransferase WbpD; Plays a role in the biosynthesis of B-band O antigen for serotype O5. Catalyzes the transfer of an acetyl group to the C-3 amino position of UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D- glucuronate (UDP-D-GlcNAc3NA) | 0.926 |
hisF2 | wbpE | PA3151 | PA3155 | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) | UDP-2-acetamido-2-dideoxy-d-ribo-hex-3-uluronic acid transaminase WbpE; Plays a role in the biosynthesis of B-band O antigen for serotype O5. Catalyzes the amination of UDP-2-acetamido-2-deoxy-3- oxo-D-glucuronic acid (UDP-3-oxo-D-GlcNAcA) to UDP-2-acetamido-3- amino-2,3-dideoxy-D-glucuronic acid (UDP-GlcNAc3NA), using L- glutamate as the preferred amine donor | 0.915 |
hisF2 | wbpG | PA3151 | PA3150 | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) | LPS biosynthesis protein WbpG | 0.989 |
hisF2 | wbpH | PA3151 | PA3149 | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) | Glycosyltransferase WbpH | 0.699 |
hisF2 | wbpI | PA3151 | PA3148 | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) | UDP-N-acetylglucosamine 2-epimerase; Plays a role in the biosynthesis of B-band O antigen for serotype O5. Catalyzes the epimerization of UDP-2,3-diacetamido- 2,3-dideoxy-alpha-D-glucuronic acid (UDP-alpha-D-GlcNAc3NAcA) to UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronic acid (UDP- alpha-D-ManNAc3NAcA). Exhibits high specificity towards the substrate as UDP-alpha-D-GlcNAc, UDP-alpha-D-GlcNAcA (UDP-2- acetamido-2-deoxy-alpha-D-glucuronic acid) and UDP-alpha-D- GlcNAc3NAc (UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucose) cannot act as substrates | 0.841 |
hisF2 | wbpJ | PA3151 | PA3147 | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) | Glycosyl transferase WbpJ | 0.755 |
hisF2 | wbpK | PA3151 | PA3146 | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) | NAD-dependent epimerase/dehydratase | 0.722 |
hisF2 | wzx | PA3151 | PA3153 | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) | O-antigen translocase | 0.942 |
wbpA | hisF2 | PA3159 | PA3151 | UDP-N-acetyl-d-glucosamine 6-dehydrogenase; Plays a role in the biosynthesis of B-band O antigen for serotype O5. Catalyzes the C-6 dehydrogenation of UDP-D-GlcNAc to UDP-N-acetylglucosaminuronic acid (UDP-D-GlcNAcA) | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) | 0.575 |
wbpA | wbpB | PA3159 | PA3158 | UDP-N-acetyl-d-glucosamine 6-dehydrogenase; Plays a role in the biosynthesis of B-band O antigen for serotype O5. Catalyzes the C-6 dehydrogenation of UDP-D-GlcNAc to UDP-N-acetylglucosaminuronic acid (UDP-D-GlcNAcA) | UDP-2-acetamido-2-deoxy-d-glucuronic acid 3-dehydrogenase WbpB; Plays a role in the biosynthesis of B-band O antigen for serotype O5. Catalyzes the NAD-dependent oxidation of UDP-N- acetylglucosaminuronic acid (UDP-D-GlcNAcA) to UDP-2-acetamido-2- deoxy-3-oxo-D-glucuronic acid (UDP-3-oxo-D-GlcNAcA). Can not use UDP-GlcNAc or UDP-GalNAc as the nucleotide sugar substrate, and can use only poorly UDP-D-glucuronic acid (UDP-GlcA). Undergoes an NAD(+) recycling mechanism using 2-oxoglutarate as an oxidant | 0.998 |
wbpA | wbpD | PA3159 | PA3156 | UDP-N-acetyl-d-glucosamine 6-dehydrogenase; Plays a role in the biosynthesis of B-band O antigen for serotype O5. Catalyzes the C-6 dehydrogenation of UDP-D-GlcNAc to UDP-N-acetylglucosaminuronic acid (UDP-D-GlcNAcA) | UDP-2-acetamido-3-amino-23-dideoxy-d-glucuronic acid N-acetyltransferase WbpD; Plays a role in the biosynthesis of B-band O antigen for serotype O5. Catalyzes the transfer of an acetyl group to the C-3 amino position of UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D- glucuronate (UDP-D-GlcNAc3NA) | 0.986 |
wbpA | wbpE | PA3159 | PA3155 | UDP-N-acetyl-d-glucosamine 6-dehydrogenase; Plays a role in the biosynthesis of B-band O antigen for serotype O5. Catalyzes the C-6 dehydrogenation of UDP-D-GlcNAc to UDP-N-acetylglucosaminuronic acid (UDP-D-GlcNAcA) | UDP-2-acetamido-2-dideoxy-d-ribo-hex-3-uluronic acid transaminase WbpE; Plays a role in the biosynthesis of B-band O antigen for serotype O5. Catalyzes the amination of UDP-2-acetamido-2-deoxy-3- oxo-D-glucuronic acid (UDP-3-oxo-D-GlcNAcA) to UDP-2-acetamido-3- amino-2,3-dideoxy-D-glucuronic acid (UDP-GlcNAc3NA), using L- glutamate as the preferred amine donor | 0.982 |
wbpA | wbpG | PA3159 | PA3150 | UDP-N-acetyl-d-glucosamine 6-dehydrogenase; Plays a role in the biosynthesis of B-band O antigen for serotype O5. Catalyzes the C-6 dehydrogenation of UDP-D-GlcNAc to UDP-N-acetylglucosaminuronic acid (UDP-D-GlcNAcA) | LPS biosynthesis protein WbpG | 0.791 |
wbpA | wbpH | PA3159 | PA3149 | UDP-N-acetyl-d-glucosamine 6-dehydrogenase; Plays a role in the biosynthesis of B-band O antigen for serotype O5. Catalyzes the C-6 dehydrogenation of UDP-D-GlcNAc to UDP-N-acetylglucosaminuronic acid (UDP-D-GlcNAcA) | Glycosyltransferase WbpH | 0.977 |
wbpA | wbpI | PA3159 | PA3148 | UDP-N-acetyl-d-glucosamine 6-dehydrogenase; Plays a role in the biosynthesis of B-band O antigen for serotype O5. Catalyzes the C-6 dehydrogenation of UDP-D-GlcNAc to UDP-N-acetylglucosaminuronic acid (UDP-D-GlcNAcA) | UDP-N-acetylglucosamine 2-epimerase; Plays a role in the biosynthesis of B-band O antigen for serotype O5. Catalyzes the epimerization of UDP-2,3-diacetamido- 2,3-dideoxy-alpha-D-glucuronic acid (UDP-alpha-D-GlcNAc3NAcA) to UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronic acid (UDP- alpha-D-ManNAc3NAcA). Exhibits high specificity towards the substrate as UDP-alpha-D-GlcNAc, UDP-alpha-D-GlcNAcA (UDP-2- acetamido-2-deoxy-alpha-D-glucuronic acid) and UDP-alpha-D- GlcNAc3NAc (UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucose) cannot act as substrates | 0.993 |
wbpA | wbpJ | PA3159 | PA3147 | UDP-N-acetyl-d-glucosamine 6-dehydrogenase; Plays a role in the biosynthesis of B-band O antigen for serotype O5. Catalyzes the C-6 dehydrogenation of UDP-D-GlcNAc to UDP-N-acetylglucosaminuronic acid (UDP-D-GlcNAcA) | Glycosyl transferase WbpJ | 0.961 |
wbpA | wbpK | PA3159 | PA3146 | UDP-N-acetyl-d-glucosamine 6-dehydrogenase; Plays a role in the biosynthesis of B-band O antigen for serotype O5. Catalyzes the C-6 dehydrogenation of UDP-D-GlcNAc to UDP-N-acetylglucosaminuronic acid (UDP-D-GlcNAcA) | NAD-dependent epimerase/dehydratase | 0.947 |
wbpA | wzx | PA3159 | PA3153 | UDP-N-acetyl-d-glucosamine 6-dehydrogenase; Plays a role in the biosynthesis of B-band O antigen for serotype O5. Catalyzes the C-6 dehydrogenation of UDP-D-GlcNAc to UDP-N-acetylglucosaminuronic acid (UDP-D-GlcNAcA) | O-antigen translocase | 0.958 |