pimE protein (Mycobacterium smegmatis) - STRING interaction network

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pimE

Mannosyltransferase; Catalyzes the alpha-1,2 addition of a mannose residue from polyprenol-phosphate-mannose (PPM) to a monoacyl phosphatidylinositol pentamannoside (AcPIM5) to generate a monoacyl phosphatidylinositol hexamannoside (AcPIM6) (377 aa)

Predicted Functional Partners:

MSMEG_4241

0.884

MSMEI_4154

0.813

MSMEG_4245

0.769

pimA

0.763

MSMEG_5130

0.749

MSMEG_5785

0.747

MSMEG_3120

0.731

MSMEG_0758

0.729

MSMEG_4250

0.705

aftA

0.705

Your Current Organism:

Mycobacterium smegmatis

NCBI taxonomy Id: 246196
Other names: Bacillus smegmatis, Bacterium smegmatis, M. smegmatis, M. smegmatis str. MC2 155, Mycobacterium paratuberculosis smegmatis, Mycobacterium smegmatis, Mycobacterium smegmatis MC2 155, Mycobacterium smegmatis str. MC2 155, Mycobacterium smegmatis strain MC2 155

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MSMEG_0758	MSMEG_3120	MSMEG_0758	MSMEG_3120	Hypothetical protein	Hypothetical protein; Catalyzes the addition of alpha-(1->6)-mannose residue	0.776
MSMEG_0758	MSMEG_4241	MSMEG_0758	MSMEG_4241	Hypothetical protein	Integral membrane protein	0.771
MSMEG_0758	MSMEG_4245	MSMEG_0758	MSMEG_4245	Hypothetical protein	Hypothetical protein; Exonuclease that cleaves single-stranded 3’ overhangs of double-stranded RNA	0.688
MSMEG_0758	MSMEG_5130	MSMEG_0758	MSMEG_5130	Hypothetical protein	Extracellular solute-binding protein; May directly or indirectly regulate the accessibility of the key branch point intermediate, monoacyl phosphatidylinositol tetramannoside (AcPIM4), to the elongating alpha-1,6 mannosyltransferases which could regulate the lipoarabinomannans (LAMs) biosynthesis	0.770
MSMEG_0758	MSMEG_5785	MSMEG_0758	MSMEG_5785	Hypothetical protein	Hypothetical protein	0.781
MSMEG_0758	pimE	MSMEG_0758	MSMEG_5149	Hypothetical protein	Mannosyltransferase; Catalyzes the alpha-1,2 addition of a mannose residue from polyprenol-phosphate-mannose (PPM) to a monoacyl phosphatidylinositol pentamannoside (AcPIM5) to generate a monoacyl phosphatidylinositol hexamannoside (AcPIM6)	0.729
MSMEG_3120	MSMEG_0758	MSMEG_3120	MSMEG_0758	Hypothetical protein; Catalyzes the addition of alpha-(1->6)-mannose residue	Hypothetical protein	0.776
MSMEG_3120	MSMEG_4245	MSMEG_3120	MSMEG_4245	Hypothetical protein; Catalyzes the addition of alpha-(1->6)-mannose residue	Hypothetical protein; Exonuclease that cleaves single-stranded 3’ overhangs of double-stranded RNA	0.688
MSMEG_3120	MSMEG_5130	MSMEG_3120	MSMEG_5130	Hypothetical protein; Catalyzes the addition of alpha-(1->6)-mannose residue	Extracellular solute-binding protein; May directly or indirectly regulate the accessibility of the key branch point intermediate, monoacyl phosphatidylinositol tetramannoside (AcPIM4), to the elongating alpha-1,6 mannosyltransferases which could regulate the lipoarabinomannans (LAMs) biosynthesis	0.591
MSMEG_3120	MSMEG_5785	MSMEG_3120	MSMEG_5785	Hypothetical protein; Catalyzes the addition of alpha-(1->6)-mannose residue	Hypothetical protein	0.736
MSMEG_3120	pimE	MSMEG_3120	MSMEG_5149	Hypothetical protein; Catalyzes the addition of alpha-(1->6)-mannose residue	Mannosyltransferase; Catalyzes the alpha-1,2 addition of a mannose residue from polyprenol-phosphate-mannose (PPM) to a monoacyl phosphatidylinositol pentamannoside (AcPIM5) to generate a monoacyl phosphatidylinositol hexamannoside (AcPIM6)	0.731
MSMEG_4241	MSMEG_0758	MSMEG_4241	MSMEG_0758	Integral membrane protein	Hypothetical protein	0.771
MSMEG_4241	MSMEG_4245	MSMEG_4241	MSMEG_4245	Integral membrane protein	Hypothetical protein; Exonuclease that cleaves single-stranded 3’ overhangs of double-stranded RNA	0.643
MSMEG_4241	MSMEG_5130	MSMEG_4241	MSMEG_5130	Integral membrane protein	Extracellular solute-binding protein; May directly or indirectly regulate the accessibility of the key branch point intermediate, monoacyl phosphatidylinositol tetramannoside (AcPIM4), to the elongating alpha-1,6 mannosyltransferases which could regulate the lipoarabinomannans (LAMs) biosynthesis	0.477
MSMEG_4241	MSMEG_5785	MSMEG_4241	MSMEG_5785	Integral membrane protein	Hypothetical protein	0.713
MSMEG_4241	MSMEI_4154	MSMEG_4241	MSMEG_4253	Integral membrane protein	Glycoside hydrolase family protein; Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 6 of a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1) to generate phosphatidyl-myo-inositol bearing alpha-1,2- and alpha-1,6-linked mannose residues (PIM2). Can also add a mannose residue to the position 2 of a phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol mannoside (PIM1) or to the position 6 of a monoacyl phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (AcPIM1) to generate a mononacyl phosphati [...]	0.561
MSMEG_4241	pimA	MSMEG_4241	MSMEG_2935	Integral membrane protein	Phosphatidylinositol alpha-mannosyltransferase; Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 2 of a phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Contrary to PimB, the mannosyltransferase PimA is unable to transfer a mannose residue to the position 6 of the phosphatidyl-myo-inositola of PIM1	0.568
MSMEG_4241	pimE	MSMEG_4241	MSMEG_5149	Integral membrane protein	Mannosyltransferase; Catalyzes the alpha-1,2 addition of a mannose residue from polyprenol-phosphate-mannose (PPM) to a monoacyl phosphatidylinositol pentamannoside (AcPIM5) to generate a monoacyl phosphatidylinositol hexamannoside (AcPIM6)	0.884
MSMEG_4245	MSMEG_0758	MSMEG_4245	MSMEG_0758	Hypothetical protein; Exonuclease that cleaves single-stranded 3’ overhangs of double-stranded RNA	Hypothetical protein	0.688
MSMEG_4245	MSMEG_3120	MSMEG_4245	MSMEG_3120	Hypothetical protein; Exonuclease that cleaves single-stranded 3’ overhangs of double-stranded RNA	Hypothetical protein; Catalyzes the addition of alpha-(1->6)-mannose residue	0.688

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