| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cj1320 | pglA | Cj1320 | Cj1125c | DegT family aminotransferase | GalNAc transferase; Adds the first GalNAc residue on to the isoprenoid- linked bacillosamine (2,4-diacetamido-2,4,6-trideoxyglucose) carrier in the N-linked protein glycosylation pathway. Acts first on the undecaprenylpyrophosphate-linked bacillosamine (Und-PP-Bac) substrate to yield the disaccharide | 0.451 |
| Cj1320 | pglC | Cj1320 | Cj1124c | DegT family aminotransferase | Galactosyltransferase; Glycosyl-1-phosphate transferase that mediates the first step in the biosynthesis of the undecaprenyl-linked heptasaccharide donor in the N-linked protein glycosylation pathway. Catalyzes the linking of uridine 5’- diphosphobacillosamine (UDP-Bac) to undecaprenyl phosphate to create the first membrane-associated intermediate undecaprenylpyrophosphate-linked Bac (Und-PP-Bac) | 0.464 |
| Cj1320 | pglD | Cj1320 | Cj1123c | DegT family aminotransferase | Acetyltransferase; Acetyltransferase that modifies the UDP-4-amino-sugar to form UDP-N,N’-diacetylbacillosamine in the N-linked protein glycosylation pathway | 0.905 |
| Cj1320 | pglF | Cj1320 | Cj1120c | DegT family aminotransferase | UDP-GlcNAc C4,6 dehydratase; C6 dehydratase involved in the bacillosamine biosynthesis pathway by generating UDP-2-acetamido-2,6-dideoxy- alpha-D-xylo-4-hexulose from UDP-N-acetyl-alpha-D-glucosamine. Involved in the N-linked protein glycosylation pathway | 0.948 |
| Cj1320 | pglH | Cj1320 | Cj1129c | DegT family aminotransferase | GalNAc transferase/polymerase; Transfers 3 terminal GalNAc residues to the carrier polyisoprene in the N-linked protein glycosylation pathway. Acts as a polymerase via a processive reaction in which intermediates do not dissociate from the enzyme and by using a single active site for multiple GalNAc transfers. Uses product inhibition to stop the enzyme from carrying out more than 3 GalNAc transfer reactions | 0.454 |
| Cj1320 | pglJ | Cj1320 | Cj1127c | DegT family aminotransferase | GalNAc transferase; Adds a GalNAc residue on to the Und-PP-Bac2,4diNAc- GalNAc disaccharide in the N-linked protein glycosylation pathway. Transfers the third sugar in the heptasaccharide biosynthesis | 0.454 |
| Cj1320 | pseC | Cj1320 | Cj1294 | DegT family aminotransferase | C4 aminotransferase; Catalyzes the second step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Uses UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4- hexulose as substrate producing UDP-4-amino-4,6-dideoxy-beta-L- AltNAc | 0.441 |
| gne | pglA | Cj1131c | Cj1125c | UDP-GlcNAc/Glc 4-epimerase | GalNAc transferase; Adds the first GalNAc residue on to the isoprenoid- linked bacillosamine (2,4-diacetamido-2,4,6-trideoxyglucose) carrier in the N-linked protein glycosylation pathway. Acts first on the undecaprenylpyrophosphate-linked bacillosamine (Und-PP-Bac) substrate to yield the disaccharide | 0.972 |
| gne | pglC | Cj1131c | Cj1124c | UDP-GlcNAc/Glc 4-epimerase | Galactosyltransferase; Glycosyl-1-phosphate transferase that mediates the first step in the biosynthesis of the undecaprenyl-linked heptasaccharide donor in the N-linked protein glycosylation pathway. Catalyzes the linking of uridine 5’- diphosphobacillosamine (UDP-Bac) to undecaprenyl phosphate to create the first membrane-associated intermediate undecaprenylpyrophosphate-linked Bac (Und-PP-Bac) | 0.914 |
| gne | pglD | Cj1131c | Cj1123c | UDP-GlcNAc/Glc 4-epimerase | Acetyltransferase; Acetyltransferase that modifies the UDP-4-amino-sugar to form UDP-N,N’-diacetylbacillosamine in the N-linked protein glycosylation pathway | 0.948 |
| gne | pglE | Cj1131c | Cj1121c | UDP-GlcNAc/Glc 4-epimerase | UDP-4-keto-6-deoxy-GlcNAc C4 aminotransferase; Aminotransferase involved in the bacillosamine biosynthesis pathway by producing UDP-4-amino-4,6-dideoxy-alpha-D- GlcNAc (UDP-2-acetamido-4-amino-2,4,6-trideoxy-alpha-D- glucopyranose), a precursor used in the production of the glycan component 2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose. Required for host colonization and virulence. Involved in the N- linked protein glycosylation pathway | 0.901 |
| gne | pglF | Cj1131c | Cj1120c | UDP-GlcNAc/Glc 4-epimerase | UDP-GlcNAc C4,6 dehydratase; C6 dehydratase involved in the bacillosamine biosynthesis pathway by generating UDP-2-acetamido-2,6-dideoxy- alpha-D-xylo-4-hexulose from UDP-N-acetyl-alpha-D-glucosamine. Involved in the N-linked protein glycosylation pathway | 0.963 |
| gne | pglG | Cj1131c | Cj1119c | UDP-GlcNAc/Glc 4-epimerase | Integral membrane protein | 0.704 |
| gne | pglH | Cj1131c | Cj1129c | UDP-GlcNAc/Glc 4-epimerase | GalNAc transferase/polymerase; Transfers 3 terminal GalNAc residues to the carrier polyisoprene in the N-linked protein glycosylation pathway. Acts as a polymerase via a processive reaction in which intermediates do not dissociate from the enzyme and by using a single active site for multiple GalNAc transfers. Uses product inhibition to stop the enzyme from carrying out more than 3 GalNAc transfer reactions | 0.979 |
| gne | pglJ | Cj1131c | Cj1127c | UDP-GlcNAc/Glc 4-epimerase | GalNAc transferase; Adds a GalNAc residue on to the Und-PP-Bac2,4diNAc- GalNAc disaccharide in the N-linked protein glycosylation pathway. Transfers the third sugar in the heptasaccharide biosynthesis | 0.980 |
| gne | pseC | Cj1131c | Cj1294 | UDP-GlcNAc/Glc 4-epimerase | C4 aminotransferase; Catalyzes the second step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Uses UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4- hexulose as substrate producing UDP-4-amino-4,6-dideoxy-beta-L- AltNAc | 0.537 |
| pglA | Cj1320 | Cj1125c | Cj1320 | GalNAc transferase; Adds the first GalNAc residue on to the isoprenoid- linked bacillosamine (2,4-diacetamido-2,4,6-trideoxyglucose) carrier in the N-linked protein glycosylation pathway. Acts first on the undecaprenylpyrophosphate-linked bacillosamine (Und-PP-Bac) substrate to yield the disaccharide | DegT family aminotransferase | 0.451 |
| pglA | gne | Cj1125c | Cj1131c | GalNAc transferase; Adds the first GalNAc residue on to the isoprenoid- linked bacillosamine (2,4-diacetamido-2,4,6-trideoxyglucose) carrier in the N-linked protein glycosylation pathway. Acts first on the undecaprenylpyrophosphate-linked bacillosamine (Und-PP-Bac) substrate to yield the disaccharide | UDP-GlcNAc/Glc 4-epimerase | 0.972 |
| pglA | pglC | Cj1125c | Cj1124c | GalNAc transferase; Adds the first GalNAc residue on to the isoprenoid- linked bacillosamine (2,4-diacetamido-2,4,6-trideoxyglucose) carrier in the N-linked protein glycosylation pathway. Acts first on the undecaprenylpyrophosphate-linked bacillosamine (Und-PP-Bac) substrate to yield the disaccharide | Galactosyltransferase; Glycosyl-1-phosphate transferase that mediates the first step in the biosynthesis of the undecaprenyl-linked heptasaccharide donor in the N-linked protein glycosylation pathway. Catalyzes the linking of uridine 5’- diphosphobacillosamine (UDP-Bac) to undecaprenyl phosphate to create the first membrane-associated intermediate undecaprenylpyrophosphate-linked Bac (Und-PP-Bac) | 0.996 |
| pglA | pglD | Cj1125c | Cj1123c | GalNAc transferase; Adds the first GalNAc residue on to the isoprenoid- linked bacillosamine (2,4-diacetamido-2,4,6-trideoxyglucose) carrier in the N-linked protein glycosylation pathway. Acts first on the undecaprenylpyrophosphate-linked bacillosamine (Und-PP-Bac) substrate to yield the disaccharide | Acetyltransferase; Acetyltransferase that modifies the UDP-4-amino-sugar to form UDP-N,N’-diacetylbacillosamine in the N-linked protein glycosylation pathway | 0.979 |
