| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| pglA | pglB | Cj1125c | Cj1126c | GalNAc transferase; Adds the first GalNAc residue on to the isoprenoid- linked bacillosamine (2,4-diacetamido-2,4,6-trideoxyglucose) carrier in the N-linked protein glycosylation pathway. Acts first on the undecaprenylpyrophosphate-linked bacillosamine (Und-PP-Bac) substrate to yield the disaccharide | Oligosaccharide transferase to N-glycosylate proteins; Oligosaccharyltransferase that catalyzes the transfer of a preassembled heptasaccharide from a lipid donor to an asparagine residue in nascent polypeptide chains, affording a beta-linked glycan to the asparagine side chain of target proteins | 0.960 |
| pglA | pglC | Cj1125c | Cj1124c | GalNAc transferase; Adds the first GalNAc residue on to the isoprenoid- linked bacillosamine (2,4-diacetamido-2,4,6-trideoxyglucose) carrier in the N-linked protein glycosylation pathway. Acts first on the undecaprenylpyrophosphate-linked bacillosamine (Und-PP-Bac) substrate to yield the disaccharide | Galactosyltransferase; Glycosyl-1-phosphate transferase that mediates the first step in the biosynthesis of the undecaprenyl-linked heptasaccharide donor in the N-linked protein glycosylation pathway. Catalyzes the linking of uridine 5’- diphosphobacillosamine (UDP-Bac) to undecaprenyl phosphate to create the first membrane-associated intermediate undecaprenylpyrophosphate-linked Bac (Und-PP-Bac) | 0.996 |
| pglA | pglD | Cj1125c | Cj1123c | GalNAc transferase; Adds the first GalNAc residue on to the isoprenoid- linked bacillosamine (2,4-diacetamido-2,4,6-trideoxyglucose) carrier in the N-linked protein glycosylation pathway. Acts first on the undecaprenylpyrophosphate-linked bacillosamine (Und-PP-Bac) substrate to yield the disaccharide | Acetyltransferase; Acetyltransferase that modifies the UDP-4-amino-sugar to form UDP-N,N’-diacetylbacillosamine in the N-linked protein glycosylation pathway | 0.979 |
| pglA | pglE | Cj1125c | Cj1121c | GalNAc transferase; Adds the first GalNAc residue on to the isoprenoid- linked bacillosamine (2,4-diacetamido-2,4,6-trideoxyglucose) carrier in the N-linked protein glycosylation pathway. Acts first on the undecaprenylpyrophosphate-linked bacillosamine (Und-PP-Bac) substrate to yield the disaccharide | UDP-4-keto-6-deoxy-GlcNAc C4 aminotransferase; Aminotransferase involved in the bacillosamine biosynthesis pathway by producing UDP-4-amino-4,6-dideoxy-alpha-D- GlcNAc (UDP-2-acetamido-4-amino-2,4,6-trideoxy-alpha-D- glucopyranose), a precursor used in the production of the glycan component 2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose. Required for host colonization and virulence. Involved in the N- linked protein glycosylation pathway | 0.946 |
| pglA | pglF | Cj1125c | Cj1120c | GalNAc transferase; Adds the first GalNAc residue on to the isoprenoid- linked bacillosamine (2,4-diacetamido-2,4,6-trideoxyglucose) carrier in the N-linked protein glycosylation pathway. Acts first on the undecaprenylpyrophosphate-linked bacillosamine (Und-PP-Bac) substrate to yield the disaccharide | UDP-GlcNAc C4,6 dehydratase; C6 dehydratase involved in the bacillosamine biosynthesis pathway by generating UDP-2-acetamido-2,6-dideoxy- alpha-D-xylo-4-hexulose from UDP-N-acetyl-alpha-D-glucosamine. Involved in the N-linked protein glycosylation pathway | 0.956 |
| pglA | pglG | Cj1125c | Cj1119c | GalNAc transferase; Adds the first GalNAc residue on to the isoprenoid- linked bacillosamine (2,4-diacetamido-2,4,6-trideoxyglucose) carrier in the N-linked protein glycosylation pathway. Acts first on the undecaprenylpyrophosphate-linked bacillosamine (Und-PP-Bac) substrate to yield the disaccharide | Integral membrane protein | 0.891 |
| pglA | pglH | Cj1125c | Cj1129c | GalNAc transferase; Adds the first GalNAc residue on to the isoprenoid- linked bacillosamine (2,4-diacetamido-2,4,6-trideoxyglucose) carrier in the N-linked protein glycosylation pathway. Acts first on the undecaprenylpyrophosphate-linked bacillosamine (Und-PP-Bac) substrate to yield the disaccharide | GalNAc transferase/polymerase; Transfers 3 terminal GalNAc residues to the carrier polyisoprene in the N-linked protein glycosylation pathway. Acts as a polymerase via a processive reaction in which intermediates do not dissociate from the enzyme and by using a single active site for multiple GalNAc transfers. Uses product inhibition to stop the enzyme from carrying out more than 3 GalNAc transfer reactions | 0.963 |
| pglA | pglI | Cj1125c | Cj1128c | GalNAc transferase; Adds the first GalNAc residue on to the isoprenoid- linked bacillosamine (2,4-diacetamido-2,4,6-trideoxyglucose) carrier in the N-linked protein glycosylation pathway. Acts first on the undecaprenylpyrophosphate-linked bacillosamine (Und-PP-Bac) substrate to yield the disaccharide | Glucosyl transferase; Glucosyltransferase that adds he final branching glucose to complete the final heptasaccharide structure in the N-linked protein glycosylation pathway | 0.979 |
| pglA | pglJ | Cj1125c | Cj1127c | GalNAc transferase; Adds the first GalNAc residue on to the isoprenoid- linked bacillosamine (2,4-diacetamido-2,4,6-trideoxyglucose) carrier in the N-linked protein glycosylation pathway. Acts first on the undecaprenylpyrophosphate-linked bacillosamine (Und-PP-Bac) substrate to yield the disaccharide | GalNAc transferase; Adds a GalNAc residue on to the Und-PP-Bac2,4diNAc- GalNAc disaccharide in the N-linked protein glycosylation pathway. Transfers the third sugar in the heptasaccharide biosynthesis | 0.993 |
| pglA | pseB | Cj1125c | Cj1293 | GalNAc transferase; Adds the first GalNAc residue on to the isoprenoid- linked bacillosamine (2,4-diacetamido-2,4,6-trideoxyglucose) carrier in the N-linked protein glycosylation pathway. Acts first on the undecaprenylpyrophosphate-linked bacillosamine (Und-PP-Bac) substrate to yield the disaccharide | UDP-GlcNAc-specific C4,6 dehydratase/C5 epimerase; Catalyzes the first step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Has both C6 dehydratase and C5 epimerase activities that result in the production of both UDP-2-acetamido-2,6-dideoxy- beta-L-arabino-4-hexulose and UDP-2-acetamido-2,6-dideoxy-alpha-D- xylo-4-hexulose | 0.405 |
| pglB | pglA | Cj1126c | Cj1125c | Oligosaccharide transferase to N-glycosylate proteins; Oligosaccharyltransferase that catalyzes the transfer of a preassembled heptasaccharide from a lipid donor to an asparagine residue in nascent polypeptide chains, affording a beta-linked glycan to the asparagine side chain of target proteins | GalNAc transferase; Adds the first GalNAc residue on to the isoprenoid- linked bacillosamine (2,4-diacetamido-2,4,6-trideoxyglucose) carrier in the N-linked protein glycosylation pathway. Acts first on the undecaprenylpyrophosphate-linked bacillosamine (Und-PP-Bac) substrate to yield the disaccharide | 0.960 |
| pglB | pglC | Cj1126c | Cj1124c | Oligosaccharide transferase to N-glycosylate proteins; Oligosaccharyltransferase that catalyzes the transfer of a preassembled heptasaccharide from a lipid donor to an asparagine residue in nascent polypeptide chains, affording a beta-linked glycan to the asparagine side chain of target proteins | Galactosyltransferase; Glycosyl-1-phosphate transferase that mediates the first step in the biosynthesis of the undecaprenyl-linked heptasaccharide donor in the N-linked protein glycosylation pathway. Catalyzes the linking of uridine 5’- diphosphobacillosamine (UDP-Bac) to undecaprenyl phosphate to create the first membrane-associated intermediate undecaprenylpyrophosphate-linked Bac (Und-PP-Bac) | 0.971 |
| pglB | pglD | Cj1126c | Cj1123c | Oligosaccharide transferase to N-glycosylate proteins; Oligosaccharyltransferase that catalyzes the transfer of a preassembled heptasaccharide from a lipid donor to an asparagine residue in nascent polypeptide chains, affording a beta-linked glycan to the asparagine side chain of target proteins | Acetyltransferase; Acetyltransferase that modifies the UDP-4-amino-sugar to form UDP-N,N’-diacetylbacillosamine in the N-linked protein glycosylation pathway | 0.975 |
| pglB | pglE | Cj1126c | Cj1121c | Oligosaccharide transferase to N-glycosylate proteins; Oligosaccharyltransferase that catalyzes the transfer of a preassembled heptasaccharide from a lipid donor to an asparagine residue in nascent polypeptide chains, affording a beta-linked glycan to the asparagine side chain of target proteins | UDP-4-keto-6-deoxy-GlcNAc C4 aminotransferase; Aminotransferase involved in the bacillosamine biosynthesis pathway by producing UDP-4-amino-4,6-dideoxy-alpha-D- GlcNAc (UDP-2-acetamido-4-amino-2,4,6-trideoxy-alpha-D- glucopyranose), a precursor used in the production of the glycan component 2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose. Required for host colonization and virulence. Involved in the N- linked protein glycosylation pathway | 0.913 |
| pglB | pglF | Cj1126c | Cj1120c | Oligosaccharide transferase to N-glycosylate proteins; Oligosaccharyltransferase that catalyzes the transfer of a preassembled heptasaccharide from a lipid donor to an asparagine residue in nascent polypeptide chains, affording a beta-linked glycan to the asparagine side chain of target proteins | UDP-GlcNAc C4,6 dehydratase; C6 dehydratase involved in the bacillosamine biosynthesis pathway by generating UDP-2-acetamido-2,6-dideoxy- alpha-D-xylo-4-hexulose from UDP-N-acetyl-alpha-D-glucosamine. Involved in the N-linked protein glycosylation pathway | 0.932 |
| pglB | pglG | Cj1126c | Cj1119c | Oligosaccharide transferase to N-glycosylate proteins; Oligosaccharyltransferase that catalyzes the transfer of a preassembled heptasaccharide from a lipid donor to an asparagine residue in nascent polypeptide chains, affording a beta-linked glycan to the asparagine side chain of target proteins | Integral membrane protein | 0.828 |
| pglB | pglH | Cj1126c | Cj1129c | Oligosaccharide transferase to N-glycosylate proteins; Oligosaccharyltransferase that catalyzes the transfer of a preassembled heptasaccharide from a lipid donor to an asparagine residue in nascent polypeptide chains, affording a beta-linked glycan to the asparagine side chain of target proteins | GalNAc transferase/polymerase; Transfers 3 terminal GalNAc residues to the carrier polyisoprene in the N-linked protein glycosylation pathway. Acts as a polymerase via a processive reaction in which intermediates do not dissociate from the enzyme and by using a single active site for multiple GalNAc transfers. Uses product inhibition to stop the enzyme from carrying out more than 3 GalNAc transfer reactions | 0.968 |
| pglB | pglI | Cj1126c | Cj1128c | Oligosaccharide transferase to N-glycosylate proteins; Oligosaccharyltransferase that catalyzes the transfer of a preassembled heptasaccharide from a lipid donor to an asparagine residue in nascent polypeptide chains, affording a beta-linked glycan to the asparagine side chain of target proteins | Glucosyl transferase; Glucosyltransferase that adds he final branching glucose to complete the final heptasaccharide structure in the N-linked protein glycosylation pathway | 0.982 |
| pglB | pglJ | Cj1126c | Cj1127c | Oligosaccharide transferase to N-glycosylate proteins; Oligosaccharyltransferase that catalyzes the transfer of a preassembled heptasaccharide from a lipid donor to an asparagine residue in nascent polypeptide chains, affording a beta-linked glycan to the asparagine side chain of target proteins | GalNAc transferase; Adds a GalNAc residue on to the Und-PP-Bac2,4diNAc- GalNAc disaccharide in the N-linked protein glycosylation pathway. Transfers the third sugar in the heptasaccharide biosynthesis | 0.969 |
| pglC | pglA | Cj1124c | Cj1125c | Galactosyltransferase; Glycosyl-1-phosphate transferase that mediates the first step in the biosynthesis of the undecaprenyl-linked heptasaccharide donor in the N-linked protein glycosylation pathway. Catalyzes the linking of uridine 5’- diphosphobacillosamine (UDP-Bac) to undecaprenyl phosphate to create the first membrane-associated intermediate undecaprenylpyrophosphate-linked Bac (Und-PP-Bac) | GalNAc transferase; Adds the first GalNAc residue on to the isoprenoid- linked bacillosamine (2,4-diacetamido-2,4,6-trideoxyglucose) carrier in the N-linked protein glycosylation pathway. Acts first on the undecaprenylpyrophosphate-linked bacillosamine (Und-PP-Bac) substrate to yield the disaccharide | 0.996 |
