wecC protein (Methanococcus maripaludis S2) - STRING interaction network

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wecC

NAD binding site-UDP-glucose/GDP-mannose dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA). Can not use NADP instead of NAD (427 aa)

Predicted Functional Partners:

wecB

0.999

MMP0357

0.999

MMP1090

0.993

MMP1091

0.939

MMP0704

0.894

MMP1088

0.856

MMP1080

0.856

MMP1089

0.851

MMP0896

0.851

MMP1076

0.850

Your Current Organism:

Methanococcus maripaludis S2

NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis S2, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MMP0357	MMP0704	MMP0357	MMP0704	UDP-N-acetylglucosamine 2-epimerase	ParA type ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	0.639
MMP0357	MMP0896	MMP0357	MMP0896	UDP-N-acetylglucosamine 2-epimerase	Polysaccharide biosynthesis protein	0.661
MMP0357	MMP1076	MMP0357	MMP1076	UDP-N-acetylglucosamine 2-epimerase	Hexapeptide repeat-containing transferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcNAc and pyrophosphate (By similarity)	0.987
MMP0357	MMP1080	MMP0357	MMP1080	UDP-N-acetylglucosamine 2-epimerase	Group 1 glycosyl transferase	0.652
MMP0357	MMP1088	MMP0357	MMP1088	UDP-N-acetylglucosamine 2-epimerase	Group 1 glycosyl transferase	0.595
MMP0357	MMP1089	MMP0357	MMP1089	UDP-N-acetylglucosamine 2-epimerase	Polysaccharide biosynthesis protein	0.661
MMP0357	MMP1090	MMP0357	MMP1090	UDP-N-acetylglucosamine 2-epimerase	NAD-dependent epimerase/dehydratase	0.701
MMP0357	wecB	MMP0357	MMP0705	UDP-N-acetylglucosamine 2-epimerase	UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues	0.807
MMP0357	wecC	MMP0357	MMP0706	UDP-N-acetylglucosamine 2-epimerase	NAD binding site-UDP-glucose/GDP-mannose dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA). Can not use NADP instead of NAD	0.999
MMP0704	MMP0357	MMP0704	MMP0357	ParA type ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	UDP-N-acetylglucosamine 2-epimerase	0.639
MMP0704	MMP0896	MMP0704	MMP0896	ParA type ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	Polysaccharide biosynthesis protein	0.692
MMP0704	MMP1080	MMP0704	MMP1080	ParA type ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	Group 1 glycosyl transferase	0.406
MMP0704	MMP1088	MMP0704	MMP1088	ParA type ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	Group 1 glycosyl transferase	0.406
MMP0704	MMP1089	MMP0704	MMP1089	ParA type ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	Polysaccharide biosynthesis protein	0.692
MMP0704	MMP1090	MMP0704	MMP1090	ParA type ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	NAD-dependent epimerase/dehydratase	0.685
MMP0704	wecB	MMP0704	MMP0705	ParA type ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues	0.850
MMP0704	wecC	MMP0704	MMP0706	ParA type ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	NAD binding site-UDP-glucose/GDP-mannose dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA). Can not use NADP instead of NAD	0.894
MMP0896	MMP0357	MMP0896	MMP0357	Polysaccharide biosynthesis protein	UDP-N-acetylglucosamine 2-epimerase	0.661
MMP0896	MMP0704	MMP0896	MMP0704	Polysaccharide biosynthesis protein	ParA type ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	0.692
MMP0896	MMP1076	MMP0896	MMP1076	Polysaccharide biosynthesis protein	Hexapeptide repeat-containing transferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcNAc and pyrophosphate (By similarity)	0.615

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