legC8 protein (Legionella pneumophila Philadelphia)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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filled nodes:
some 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

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Score

legC8

Coiled-coil containing protein (636 aa)

Predicted Functional Partners:

lpg2863

0.558

lpg2867

0.413

priA

0.413

lpg2865

0.413

lpg2864

0.413

Your Current Organism:

Legionella pneumophila Philadelphia

NCBI taxonomy Id: 272624
Other names: L. pneumophila subsp. pneumophila, L. pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila Philadelphia, Legionella pneumophila subsp. pneumophila, Legionella pneumophila subsp. pneumophila str. Philadelphia 1, Legionella pneumophila subsp. pneumophila strain Philadelphia 1

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
legC8	lpg2863	lpg2862	lpg2863	Coiled-coil containing protein	Pteridine reductase	0.558
legC8	lpg2864	lpg2862	lpg2864	Coiled-coil containing protein	Hypothetical protein	0.413
legC8	lpg2865	lpg2862	lpg2865	Coiled-coil containing protein	6-pyruvoyl tetrahydrobiopterin synthase	0.413
legC8	lpg2867	lpg2862	lpg2867	Coiled-coil containing protein	Hypothetical protein	0.413
legC8	priA	lpg2862	lpg2866	Coiled-coil containing protein	Primosomal protein N’; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	0.413
lpg2863	legC8	lpg2863	lpg2862	Pteridine reductase	Coiled-coil containing protein	0.558
lpg2863	lpg2864	lpg2863	lpg2864	Pteridine reductase	Hypothetical protein	0.751
lpg2863	lpg2865	lpg2863	lpg2865	Pteridine reductase	6-pyruvoyl tetrahydrobiopterin synthase	0.611
lpg2863	lpg2867	lpg2863	lpg2867	Pteridine reductase	Hypothetical protein	0.620
lpg2863	priA	lpg2863	lpg2866	Pteridine reductase	Primosomal protein N’; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	0.620
lpg2864	legC8	lpg2864	lpg2862	Hypothetical protein	Coiled-coil containing protein	0.413
lpg2864	lpg2863	lpg2864	lpg2863	Hypothetical protein	Pteridine reductase	0.751
lpg2864	lpg2865	lpg2864	lpg2865	Hypothetical protein	6-pyruvoyl tetrahydrobiopterin synthase	0.859
lpg2864	lpg2867	lpg2864	lpg2867	Hypothetical protein	Hypothetical protein	0.862
lpg2864	priA	lpg2864	lpg2866	Hypothetical protein	Primosomal protein N’; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	0.865
lpg2865	legC8	lpg2865	lpg2862	6-pyruvoyl tetrahydrobiopterin synthase	Coiled-coil containing protein	0.413
lpg2865	lpg2863	lpg2865	lpg2863	6-pyruvoyl tetrahydrobiopterin synthase	Pteridine reductase	0.611
lpg2865	lpg2864	lpg2865	lpg2864	6-pyruvoyl tetrahydrobiopterin synthase	Hypothetical protein	0.859
lpg2865	lpg2867	lpg2865	lpg2867	6-pyruvoyl tetrahydrobiopterin synthase	Hypothetical protein	0.862
lpg2865	priA	lpg2865	lpg2866	6-pyruvoyl tetrahydrobiopterin synthase	Primosomal protein N’; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	0.864

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