node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HP_0114 | HP_0326 | HP0114 | HP0326 | Hypothetical protein | CMP-N-acetylneuraminic acid synthetase; Catalyzes the fourth and sixth steps in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. The C-terminus mediates the fourth step of the pathway and catalyzes the removal of UDP from C-1 of UDP-2,4- diacetamido-2,4,6-trideoxy-beta-L-altropyranose forming 2,4- diacetamido-2,4,6-trideoxy-beta-L-altropyranose. The N-terminal part mediates the last step of the pathway by mediating activation of pseudaminic acid with CMP by forming CMP-pseudaminic acid | 0.624 |
HP_0114 | pseB | HP0114 | HP0840 | Hypothetical protein | flaA1 protein; Catalyzes the first step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Has both C6 dehydratase and C5 epimerase activities that result in the production of both UDP-2-acetamido-2,6-dideoxy- beta-L-arabino-4-hexulose and UDP-2-acetamido-2,6-dideoxy-alpha-D- xylo-4-hexulose | 0.772 |
HP_0114 | pseC | HP0114 | HP0366 | Hypothetical protein | Spore coat polysaccharide biosynthesis protein C; Catalyzes the second step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Uses UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4- hexulose as substrate producing UDP-4-amino-4,6-dideoxy-beta-L- AltNAc | 0.679 |
HP_0114 | pseH | HP0114 | HP0327 | Hypothetical protein | Flagellar protein FlaG; Catalyzes the third step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Mediates N-4 acetylation of UDP-4-amino-4,6-dideoxy- beta-L-AltNAc to form UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L- altropyranose | 0.756 |
HP_0114 | pseI | HP0114 | HP0178 | Hypothetical protein | Sialic acid synthase; Catalyzes the fifth step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Catalyzes the condensation of phosphoenolpyruvate with 2,4-diacetamido-2,4,6-trideoxy-beta-l-altropyranose, forming pseudaminic acid (By similarity) | 0.885 |
HP_0326 | HP_0114 | HP0326 | HP0114 | CMP-N-acetylneuraminic acid synthetase; Catalyzes the fourth and sixth steps in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. The C-terminus mediates the fourth step of the pathway and catalyzes the removal of UDP from C-1 of UDP-2,4- diacetamido-2,4,6-trideoxy-beta-L-altropyranose forming 2,4- diacetamido-2,4,6-trideoxy-beta-L-altropyranose. The N-terminal part mediates the last step of the pathway by mediating activation of pseudaminic acid with CMP by forming CMP-pseudaminic acid | Hypothetical protein | 0.624 |
HP_0326 | flgH | HP0326 | HP0325 | CMP-N-acetylneuraminic acid synthetase; Catalyzes the fourth and sixth steps in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. The C-terminus mediates the fourth step of the pathway and catalyzes the removal of UDP from C-1 of UDP-2,4- diacetamido-2,4,6-trideoxy-beta-L-altropyranose forming 2,4- diacetamido-2,4,6-trideoxy-beta-L-altropyranose. The N-terminal part mediates the last step of the pathway by mediating activation of pseudaminic acid with CMP by forming CMP-pseudaminic acid | Flagellar basal body L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation | 0.897 |
HP_0326 | pseB | HP0326 | HP0840 | CMP-N-acetylneuraminic acid synthetase; Catalyzes the fourth and sixth steps in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. The C-terminus mediates the fourth step of the pathway and catalyzes the removal of UDP from C-1 of UDP-2,4- diacetamido-2,4,6-trideoxy-beta-L-altropyranose forming 2,4- diacetamido-2,4,6-trideoxy-beta-L-altropyranose. The N-terminal part mediates the last step of the pathway by mediating activation of pseudaminic acid with CMP by forming CMP-pseudaminic acid | flaA1 protein; Catalyzes the first step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Has both C6 dehydratase and C5 epimerase activities that result in the production of both UDP-2-acetamido-2,6-dideoxy- beta-L-arabino-4-hexulose and UDP-2-acetamido-2,6-dideoxy-alpha-D- xylo-4-hexulose | 0.672 |
HP_0326 | pseC | HP0326 | HP0366 | CMP-N-acetylneuraminic acid synthetase; Catalyzes the fourth and sixth steps in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. The C-terminus mediates the fourth step of the pathway and catalyzes the removal of UDP from C-1 of UDP-2,4- diacetamido-2,4,6-trideoxy-beta-L-altropyranose forming 2,4- diacetamido-2,4,6-trideoxy-beta-L-altropyranose. The N-terminal part mediates the last step of the pathway by mediating activation of pseudaminic acid with CMP by forming CMP-pseudaminic acid | Spore coat polysaccharide biosynthesis protein C; Catalyzes the second step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Uses UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4- hexulose as substrate producing UDP-4-amino-4,6-dideoxy-beta-L- AltNAc | 0.634 |
HP_0326 | pseH | HP0326 | HP0327 | CMP-N-acetylneuraminic acid synthetase; Catalyzes the fourth and sixth steps in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. The C-terminus mediates the fourth step of the pathway and catalyzes the removal of UDP from C-1 of UDP-2,4- diacetamido-2,4,6-trideoxy-beta-L-altropyranose forming 2,4- diacetamido-2,4,6-trideoxy-beta-L-altropyranose. The N-terminal part mediates the last step of the pathway by mediating activation of pseudaminic acid with CMP by forming CMP-pseudaminic acid | Flagellar protein FlaG; Catalyzes the third step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Mediates N-4 acetylation of UDP-4-amino-4,6-dideoxy- beta-L-AltNAc to form UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L- altropyranose | 0.950 |
HP_0326 | pseI | HP0326 | HP0178 | CMP-N-acetylneuraminic acid synthetase; Catalyzes the fourth and sixth steps in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. The C-terminus mediates the fourth step of the pathway and catalyzes the removal of UDP from C-1 of UDP-2,4- diacetamido-2,4,6-trideoxy-beta-L-altropyranose forming 2,4- diacetamido-2,4,6-trideoxy-beta-L-altropyranose. The N-terminal part mediates the last step of the pathway by mediating activation of pseudaminic acid with CMP by forming CMP-pseudaminic acid | Sialic acid synthase; Catalyzes the fifth step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Catalyzes the condensation of phosphoenolpyruvate with 2,4-diacetamido-2,4,6-trideoxy-beta-l-altropyranose, forming pseudaminic acid (By similarity) | 0.998 |
HP_1240 | mrp | HP1240 | HP0207 | Maf-like protein | ATP-binding protein (mpr); Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP | 0.835 |
HP_1240 | pseB | HP1240 | HP0840 | Maf-like protein | flaA1 protein; Catalyzes the first step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Has both C6 dehydratase and C5 epimerase activities that result in the production of both UDP-2-acetamido-2,6-dideoxy- beta-L-arabino-4-hexulose and UDP-2-acetamido-2,6-dideoxy-alpha-D- xylo-4-hexulose | 0.453 |
HP_1240 | pseC | HP1240 | HP0366 | Maf-like protein | Spore coat polysaccharide biosynthesis protein C; Catalyzes the second step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Uses UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4- hexulose as substrate producing UDP-4-amino-4,6-dideoxy-beta-L- AltNAc | 0.538 |
HP_1240 | pseH | HP1240 | HP0327 | Maf-like protein | Flagellar protein FlaG; Catalyzes the third step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Mediates N-4 acetylation of UDP-4-amino-4,6-dideoxy- beta-L-AltNAc to form UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L- altropyranose | 0.757 |
HP_1240 | pseI | HP1240 | HP0178 | Maf-like protein | Sialic acid synthase; Catalyzes the fifth step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Catalyzes the condensation of phosphoenolpyruvate with 2,4-diacetamido-2,4,6-trideoxy-beta-l-altropyranose, forming pseudaminic acid (By similarity) | 0.833 |
flgH | HP_0326 | HP0325 | HP0326 | Flagellar basal body L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation | CMP-N-acetylneuraminic acid synthetase; Catalyzes the fourth and sixth steps in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. The C-terminus mediates the fourth step of the pathway and catalyzes the removal of UDP from C-1 of UDP-2,4- diacetamido-2,4,6-trideoxy-beta-L-altropyranose forming 2,4- diacetamido-2,4,6-trideoxy-beta-L-altropyranose. The N-terminal part mediates the last step of the pathway by mediating activation of pseudaminic acid with CMP by forming CMP-pseudaminic acid | 0.897 |
flgH | pseB | HP0325 | HP0840 | Flagellar basal body L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation | flaA1 protein; Catalyzes the first step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Has both C6 dehydratase and C5 epimerase activities that result in the production of both UDP-2-acetamido-2,6-dideoxy- beta-L-arabino-4-hexulose and UDP-2-acetamido-2,6-dideoxy-alpha-D- xylo-4-hexulose | 0.548 |
flgH | pseH | HP0325 | HP0327 | Flagellar basal body L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation | Flagellar protein FlaG; Catalyzes the third step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Mediates N-4 acetylation of UDP-4-amino-4,6-dideoxy- beta-L-AltNAc to form UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L- altropyranose | 0.826 |
mrp | HP_1240 | HP0207 | HP1240 | ATP-binding protein (mpr); Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP | Maf-like protein | 0.835 |