| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MJ0122 | eif2a | MJ_0122 | MJ_0117 | Translation initiation factor IF-2; Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO (By similarity) | Translation initiation factor IF-2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA | 0.993 |
| MJ0122 | eif2b | MJ_0122 | MJ_0097 | Translation initiation factor IF-2; Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO (By similarity) | Translation initiation factor IF-2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA | 0.989 |
| MJ0122 | eif2g | MJ_0122 | MJ_1261 | Translation initiation factor IF-2; Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO (By similarity) | Translation initiation factor IF-2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA | 0.983 |
| MJ0122 | glmU | MJ_0122 | MJ_1101 | Translation initiation factor IF-2; Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO (By similarity) | Glucose-1-phosphate thymidylyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcNAc and pyrophosphate. Also catalyzes the reverse reaction, i.e. the cleavage of UDP-GlcNAc with pyrophosphate to form UTP and GlcNAc-1-P. To a lesser extent, is also able to use dUTP or dTTP as the nucleotide substrate, but not CTP, ATP or GTP | 0.993 |
| dut | glmM | MJ_1102 | MJ_1100 | Deoxycytidine triphosphate deaminase; This enzyme is involved in nucleotide metabolism- it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA | Phosphomannomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate | 0.860 |
| dut | glmS | MJ_1102 | MJ_1420 | Deoxycytidine triphosphate deaminase; This enzyme is involved in nucleotide metabolism- it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source | 0.603 |
| dut | glmU | MJ_1102 | MJ_1101 | Deoxycytidine triphosphate deaminase; This enzyme is involved in nucleotide metabolism- it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA | Glucose-1-phosphate thymidylyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcNAc and pyrophosphate. Also catalyzes the reverse reaction, i.e. the cleavage of UDP-GlcNAc with pyrophosphate to form UTP and GlcNAc-1-P. To a lesser extent, is also able to use dUTP or dTTP as the nucleotide substrate, but not CTP, ATP or GTP | 0.911 |
| dut | manB | MJ_1102 | MJ_0399 | Deoxycytidine triphosphate deaminase; This enzyme is involved in nucleotide metabolism- it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA | Phosphomannomutase; Catalyzes the formation of mannose-1-P from mannose-6-P. Can also use glucose-1-P | 0.482 |
| dut | pol | MJ_1102 | MJ_0885 | Deoxycytidine triphosphate deaminase; This enzyme is involved in nucleotide metabolism- it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA | DNA polymerase B1 | 0.740 |
| dut | wecB | MJ_1102 | MJ_1504 | Deoxycytidine triphosphate deaminase; This enzyme is involved in nucleotide metabolism- it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA | Lipopolysaccharide biosynthesis protein WbpI; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues | 0.731 |
| eif2a | MJ0122 | MJ_0117 | MJ_0122 | Translation initiation factor IF-2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA | Translation initiation factor IF-2; Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO (By similarity) | 0.993 |
| eif2a | eif2b | MJ_0117 | MJ_0097 | Translation initiation factor IF-2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA | Translation initiation factor IF-2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA | 0.999 |
| eif2a | eif2g | MJ_0117 | MJ_1261 | Translation initiation factor IF-2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA | Translation initiation factor IF-2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA | 0.999 |
| eif2a | glmU | MJ_0117 | MJ_1101 | Translation initiation factor IF-2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA | Glucose-1-phosphate thymidylyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcNAc and pyrophosphate. Also catalyzes the reverse reaction, i.e. the cleavage of UDP-GlcNAc with pyrophosphate to form UTP and GlcNAc-1-P. To a lesser extent, is also able to use dUTP or dTTP as the nucleotide substrate, but not CTP, ATP or GTP | 0.989 |
| eif2b | MJ0122 | MJ_0097 | MJ_0122 | Translation initiation factor IF-2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA | Translation initiation factor IF-2; Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO (By similarity) | 0.989 |
| eif2b | eif2a | MJ_0097 | MJ_0117 | Translation initiation factor IF-2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA | Translation initiation factor IF-2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA | 0.999 |
| eif2b | eif2g | MJ_0097 | MJ_1261 | Translation initiation factor IF-2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA | Translation initiation factor IF-2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA | 0.999 |
| eif2b | glmU | MJ_0097 | MJ_1101 | Translation initiation factor IF-2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA | Glucose-1-phosphate thymidylyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcNAc and pyrophosphate. Also catalyzes the reverse reaction, i.e. the cleavage of UDP-GlcNAc with pyrophosphate to form UTP and GlcNAc-1-P. To a lesser extent, is also able to use dUTP or dTTP as the nucleotide substrate, but not CTP, ATP or GTP | 0.989 |
| eif2g | MJ0122 | MJ_1261 | MJ_0122 | Translation initiation factor IF-2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA | Translation initiation factor IF-2; Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO (By similarity) | 0.983 |
| eif2g | eif2a | MJ_1261 | MJ_0117 | Translation initiation factor IF-2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA | Translation initiation factor IF-2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA | 0.999 |
