wecB protein (Methanococcus maripaludis S2) - STRING interaction network

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wecB

UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues (366 aa)

Predicted Functional Partners:

wecC

0.999

MMP0353

0.988

MMP1076

0.987

MMP1090

0.884

MMP1089

0.869

MMP0896

0.869

MMP1083

0.867

wbpG

0.863

MMP1080

0.862

hisH2

0.862

Your Current Organism:

Methanococcus maripaludis S2

NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis S2, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MMP0353	MMP0896	MMP0353	MMP0896	UDP-glucose/GDP-mannose dehydrogenase-like protein	Polysaccharide biosynthesis protein	0.616
MMP0353	MMP1076	MMP0353	MMP1076	UDP-glucose/GDP-mannose dehydrogenase-like protein	Hexapeptide repeat-containing transferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcNAc and pyrophosphate (By similarity)	0.850
MMP0353	MMP1080	MMP0353	MMP1080	UDP-glucose/GDP-mannose dehydrogenase-like protein	Group 1 glycosyl transferase	0.666
MMP0353	MMP1089	MMP0353	MMP1089	UDP-glucose/GDP-mannose dehydrogenase-like protein	Polysaccharide biosynthesis protein	0.616
MMP0353	MMP1090	MMP0353	MMP1090	UDP-glucose/GDP-mannose dehydrogenase-like protein	NAD-dependent epimerase/dehydratase	0.982
MMP0353	wecB	MMP0353	MMP0705	UDP-glucose/GDP-mannose dehydrogenase-like protein	UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues	0.988
MMP0896	MMP0353	MMP0896	MMP0353	Polysaccharide biosynthesis protein	UDP-glucose/GDP-mannose dehydrogenase-like protein	0.616
MMP0896	MMP1076	MMP0896	MMP1076	Polysaccharide biosynthesis protein	Hexapeptide repeat-containing transferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcNAc and pyrophosphate (By similarity)	0.615
MMP0896	MMP1080	MMP0896	MMP1080	Polysaccharide biosynthesis protein	Group 1 glycosyl transferase	0.685
MMP0896	MMP1083	MMP0896	MMP1083	Polysaccharide biosynthesis protein	Imidazole glycerol phosphate synthase subunit HisF	0.517
MMP0896	MMP1090	MMP0896	MMP1090	Polysaccharide biosynthesis protein	NAD-dependent epimerase/dehydratase	0.613
MMP0896	hisH2	MMP0896	MMP1082	Polysaccharide biosynthesis protein	Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)	0.467
MMP0896	wecB	MMP0896	MMP0705	Polysaccharide biosynthesis protein	UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues	0.869
MMP0896	wecC	MMP0896	MMP0706	Polysaccharide biosynthesis protein	NAD binding site-UDP-glucose/GDP-mannose dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA). Can not use NADP instead of NAD	0.851
MMP1076	MMP0353	MMP1076	MMP0353	Hexapeptide repeat-containing transferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcNAc and pyrophosphate (By similarity)	UDP-glucose/GDP-mannose dehydrogenase-like protein	0.850
MMP1076	MMP0896	MMP1076	MMP0896	Hexapeptide repeat-containing transferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcNAc and pyrophosphate (By similarity)	Polysaccharide biosynthesis protein	0.615
MMP1076	MMP1080	MMP1076	MMP1080	Hexapeptide repeat-containing transferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcNAc and pyrophosphate (By similarity)	Group 1 glycosyl transferase	0.966
MMP1076	MMP1083	MMP1076	MMP1083	Hexapeptide repeat-containing transferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcNAc and pyrophosphate (By similarity)	Imidazole glycerol phosphate synthase subunit HisF	0.776
MMP1076	MMP1089	MMP1076	MMP1089	Hexapeptide repeat-containing transferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcNAc and pyrophosphate (By similarity)	Polysaccharide biosynthesis protein	0.615
MMP1076	MMP1090	MMP1076	MMP1090	Hexapeptide repeat-containing transferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcNAc and pyrophosphate (By similarity)	NAD-dependent epimerase/dehydratase	0.982

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