• Version:
  • 10.5 (archived version)
STRINGSTRING

Database Knowledge

Relevant datasets in Homo sapiens:

curated complex (Gene Ontology)
mitochondrial respiratory chain complex I
 MT-ND5  
 MT-ND4  
 MT-ND3  
 MT-ND2  
 MT-ND1  
 NDUFA1  
 NDUFS3  
 NDUFV1  
 NDUFV2   [... and 39 other proteins]
curated complex (Gene Ontology)
respiratory chain complex I
 MT-ND5  
 MT-ND4  
 MT-ND3  
 MT-ND2  
 MT-ND1  
 NDUFA1  
 NDUFS3  
 NDUFV1  
 NDUFV2   [... and 39 other proteins]
curated pathway
Complex: 815kDa complex
 MT-ND6  
 MT-ND5  
 MT-ND4  
 MT-ND3  
 MT-ND2  
 MT-ND1  
 NDUFA1  
 NDUFS3  
 NDUFAF3   [... and 35 other proteins]
curated complex (Gene Ontology)
NADH dehydrogenase complex
 MT-ND5  
 MT-ND4  
 MT-ND3  
 MT-ND2  
 MT-ND1  
 NDUFA1  
 NDUFS3  
 NDUFV1  
 NDUFV2   [... and 39 other proteins]
curated pathway
Complex: 815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1)
 MT-ND6  
 MT-ND5  
 MT-ND4  
 MT-ND3  
 MT-ND2  
 MT-ND1  
 NDUFA1  
 NDUFS3   [... and 26 other proteins]
curated pathway
Complex: 550kDa complex
 MT-ND6  
 MT-ND3  
 MT-ND2  
 MT-ND1  
 NDUFA1  
 NDUFS3  
 NDUFAF3   [... and 35 other proteins]
curated pathway
Complex: 550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1)
 MT-ND6  
 MT-ND3  
 MT-ND2  
 MT-ND1  
 NDUFA1  
 NDUFS3   [... and 26 other proteins]
annotated pathway (KEGG)
Name: Non-alcoholic fatty liver disease (NAFLD)
 NDUFA1  
 NDUFS3  
 NDUFV1  
 NDUFV2   [... and 143 other proteins]
annotated pathway (KEGG)
Name: Alzheimer's disease
 NDUFA1  
 NDUFS3  
 NDUFV1  
 NDUFV2   [... and 160 other proteins]
annotated pathway (KEGG)
Name: Huntington's disease
 NDUFA1  
 NDUFS3  
 NDUFV1  
 NDUFV2   [... and 187 other proteins]
[truncated after 10 items]

Relevant information transferred from other organisms:

curated complex (Gene Ontology)
plasma membrane respiratory chain complex I
Escherichia coli K12 DH10B: 
/
 nuoM  
/
/
 nuoL  
 nuoA  
 nuoH  
 nuoC  
 nuoE   [... and 7 other proteins]
curated pathway
Biochemical Reaction: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I
Mus musculus: 
 mt-Nd6  
 mt-Nd4  
/
 mt-Nd5  
/
 Gm4076  
 mt-Nd3  
 mt-Nd1  
 Ndufa1  
 Ndufs3  
 Ndufaf3  
 Ndufv1  
 Ndufv2   [... and 40 other proteins]
curated pathway
Complex: 980kDa complex (name copied from entity in Homo sapiens)
Mus musculus: 
 mt-Nd6  
 mt-Nd4  
/
 mt-Nd5  
/
 Gm4076  
 mt-Nd3  
 mt-Nd1  
 Ndufa1  
 Ndufs3  
 Ndufaf3  
 Ndufv1  
 Ndufv2   [... and 40 other proteins]
curated pathway
Pathway: Complex I biogenesis
Mus musculus: 
 mt-Nd6  
 mt-Nd4  
/
 mt-Nd5  
/
 Gm4076  
 mt-Nd3  
 mt-Nd1  
 Ndufa1  
 Ndufs3  
 Ndufaf3  
 Ndufv1  
 Ndufv2   [... and 41 other proteins]
curated pathway
Catalysis: Complex I oxidises NADH to NAD+, reduces CoQ to QH2
Gallus gallus: 
 ND6  
 ND4  
/
 ND2  
/
 ND5  
 ND3  
 ND1  
 NDUFA1  
 NDUFS3  
 NDUFV1  
 NDUFV2   [... and 21 other proteins]
curated pathway
Complex: Complex I (name copied from entity in Homo sapiens)
Gallus gallus: 
 ND6  
 ND4  
/
 ND2  
/
 ND5  
 ND3  
 ND1  
 NDUFA1  
 NDUFS3  
 NDUFV1  
 NDUFV2   [... and 21 other proteins]
curated pathway
Complex: 980kDa complex (name copied from entity in Homo sapiens)
Gallus gallus: 
 ND6  
 ND4  
/
 ND5  
/
 ND2  
 ND3  
 ND1  
 NDUFA1  
 NDUFS3  
 NDUFV1  
 NDUFV2   [... and 28 other proteins]
curated pathway
Pathway: Complex I biogenesis
Gallus gallus: 
 ND6  
 ND4  
/
 ND5  
/
 ND2  
 ND3  
 ND1  
 NDUFA1  
 NDUFS3  
 NDUFV1  
 NDUFV2   [... and 29 other proteins]
curated pathway
Catalysis: Complex I oxidises NADH to NAD+, reduces CoQ to QH2
Mus musculus: 
 mt-Nd6  
 mt-Nd4  
/
 mt-Nd5  
/
 Gm4076  
 mt-Nd3  
 mt-Nd1  
 Ndufa1  
 Ndufs3  
 Ndufv1  
 Ndufv2   [... and 32 other proteins]
curated pathway
Complex: Complex I (name copied from entity in Homo sapiens)
Mus musculus: 
 mt-Nd6  
 mt-Nd4  
/
 mt-Nd5  
/
 Gm4076  
 mt-Nd3  
 mt-Nd1  
 Ndufa1  
 Ndufs3  
 Ndufv1  
 Ndufv2   [... and 32 other proteins]
[truncated after 10 items]
Functional enrichments in your set of proteinsNote: some enrichments may be expected here (why?)
Enrichment analysis is still ongoing, please wait ...
Statistical background
For the above enrichment analysis,
the following statistical background
is assumed:
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